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doi:10.1016/s0307-4412(97)00167-2

Nrf2/Keap1/ARE Redox Regulatory Pathway In response to oxidative or xenobiotic stress, Nrf2 dissociates from its inhibitor Keap1, translocates to the nucleus, and binds antioxidant response elements (ARE) to induce expression of genes involved in antioxidant defense and GSH biosynthesis (41)

Bose P, Masarova L, Pemmaraju N, Bledsoe SD, Daver NG, Jabbour EJ, Kadia TM, Estrov ZE, Kornblau SM, Andreeff M , Jain N, Cortes JE, Borthakur G, Alvarado Y, Richie MA, Dobbins MH, McCrackin SA, Zhou L, Pierce SA, Wang X, Pike AM, Garcia-Manero G, Kantarjian HM, Verstovsek S

Glutathione Levels and Immune Responses in Tuberculosis Patients